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On 1 August 2004, we received this note from E.V. of Toronto, Ontario, Canada, concerning their use of sucralose.
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"Some of the reported effects may be explainable in physiological terms. Since Splenda is a non-digestible sugar, it falls into the class of fibers and, as such, is consumed by colonic bacteria causing gas and attendant bloating. This should be viewed as a positive development because it improves colonic health, just as fructo-oligosaccharides (FOS, insulin) do. In all likelihood, many users consume insufficient amouns of fiber and are not used to it.
Secondly, there may be a training effect, where the body anticipates the influx of real sugar and reacts by raising insulin levels in order to deal with it. Since no digestible sugar arrives, the result is momentary hypoglycemia resulting in feeling of fatigure and even depression. It may also explain increased sugar cravings. Both effects are likely to dissipate over time."
Thank you E.V. for sharing your story with our visitors.
Editor's Note: Our response to E.V. is as follows: While we agree that your logic is correct, it probably doesn't apply to the majority of persons suffering from the ill effects of sucralose. Many of these people experience problems that don't relate to a spike or drop in insulin leveles, experience the symptoms for sustained periods of time exceeding that required to bring insulin levels back to normal, and experience the symptoms for periods of months or even years. However, the lack of fiber is definitely a problem for many people trying out the new high protein diets.
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